BSAC Spring Conference 2020

Into Clinical Practice
- Bridging the gap between science, policy and effective antimicrobial use

CANCELLED

16-17 March 2020

Queen Elizabeth Conference Centre, Westminster, London

Conference archives

View and watch resources from previous conferences.

BSAC Spring Conference 2019
Global views, local problems: Innovative solutions to AMR and infection challenges

21 – 22 March 2019, The ICC, 8 Centenary Square, Birmingham, B1 2EA

Please find below links to the presentation slides and poster abstracts from the 2019 BSAC Spring Conference

Thursday 21st March

PLENARY SESSION: SPOTLIGHT ON AMR AND INFECTION MANAGEMENT

Shortages, stockouts and scarcity: The issues facing the security of antibiotic supply and the role for pharmaceutical companies

Dr Deidre Cogan, Writer/Editor, Access to Medicine Foundation

The link between social and economic deprivation and AMR - via Skype

Professor Ramanan Laxminarayan, Director and Senior Fellow, The Center for Disease Dynamics, Economics & Policy, Washington DC

Innovation and AMR

Professor Dilip Nathwani OBE, Director, Academic Health Sciences Partnership [AHSP] in Tayside, Consultant Physician and Honorary Professor of Infection, Ninewells Hospital and Medical School, Dundee

Tailoring stewardship to context: Drivers and patterns of antibiotic prescribing and consumption in rural China

Professor Helen Lambert, Professor of Medical Anthropology, Bristol Medical School, University of Bristol

KEYNOTE PRESENTATION: INAUGURAL JAC ANNUAL LECTURE

UK Initiatives to Reduce Inappropriate Antibiotic Prescribing

Professor Alan Johnson, Head of Surveillance in the Healthcare-Associated Infection & Antimicrobial Resistance (HCAI & AMR) Division of the National Infection Service, Public Health England

Parallel Session One: Here now and almost here! Infection management of the future

Bacteriophages - how significant will their impact be?

Professor Martha Clokie, Professor of Microbiology, University of Leicester

It all gone to worms - the role of odilorhabdins!

Dr Philippe Villain-Guillot, CEO, Nosopharm

Parallel Session Two: Diagnostics

Role of digital PCR in high accuracy measurement in infectious diseases

Dr Denise O’Sullivan, Science Leader, LGC

Inter-laboratory study comparing bacterial AMR predictions from WGS data

Dr Ronan Doyle, Research Associate, Great Ormond Street Hospital NHS Foundation Trust

Developing metrology to support antimicrobial discovery, validation and screening

Professor Max Ryadnov, Biometrology Leader, National Physical Laboratory

Standardisation of procalcitonin measurement

Dr Amandine Boeuf, Researcher, Laboratoire de Métrologie et d’Essai (LNE)

SPONSORED SESSION: MOTIVATING CHANGE IN THE MDR-GNB TREATMENT PATHWAY – ARE WE TOO LATE?

State of the nation - The problems and challenges for the treatment of patients with MDR Gram Negative pathogens

Professor Peter Hawkey, University of Birmingham

Life after a MDR GNB Outbreak - Treatment pathway change in Manchester and emerging data

Dr Louise Sweeney, Central Manchester University Hospitals NHS Trust

PLENARY SESSION: GARROD LECTURE

Garrod Lecture 2019: MDR efflux in Gram negative bacteria - how understanding resistance led to a new tool for drug discovery

Professor Laura Piddock, University of Birmingham and GARDP

Global Knowledge exchange - Antimicrobial Resistance and Stewardship

Professor Dilip Nathwani OBE, Director, Academic Health Sciences Partnership [AHSP] in Tayside, Consultant Physician and Honorary Professor of Infection, Ninewells Hospital and Medical School, Dundee

PLENARY SESSION: KEY INFLUENCING PAPERS: WHAT HAS INFLUENCED AND IMPACTED PRACTICE IN THE PAST FIVE YEARS?

Stewardship

Professor Dilip Nathwani OBE, Director, Academic Health Sciences Partnership [AHSP] in Tayside, Consultant Physician and Honorary Professor of Infection, Ninewells Hospital and Medical School, Dundee

Diagnostics

Dr Till Bachmann, Reader in Personalised Medicine in Infectious Diseases, Deputy Head of Division of Infection and Pathway Medicine, University of Edinburgh

Behaviour Change & AMR

Dr Esmita Charani, Senior Lead Pharmacist, Imperial College London

Friday 22nd March

PLENARY SESSION: CLINICAL LESSONS & FREE PAPERS SELECTED FROM ABSTRACTS

Managing self-limiting infections in community pharmacies: a cluster randomised controlled trial

Ms Eno Umoh, Public Health England

Ceftazidime/avibactam in paediatrics: Challenges and treatment outcomes

Mrs Frances Garraghan, Lead antimicrobial pharmacist, Manchester University Foundation Trust

Educating the workforce in AMR – too many gimmicks or coming up trumps?

Dr Angharad Davies, Clinical Associate Professor, Swansea University Medical School

Why do dentists prescribe antibiotics for adults with toothache or infection?

Mrs Wendy Thompson, University of Leeds

Structuring the Management of High-Risk Skin Infections: A Model Care Pathway

Dr Abid Hussain, University Hospitals of Birmingham NHS Foundation Trust

PLENARY SESSION: GENOMIC & MOLECULAR DIAGNOSTICS

Current and future directions for rapid AMR diagnostics

Dr Till Bachmann, Reader in Personalised Medicine in Infectious Diseases, Deputy Head of Division of Infection and Pathway Medicine, University of Edinburgh

MALDI-TOF-MS - beyond species ID

Dr Belén Rodriguez Sanchez, Hospital Gregorio Maranon, Madrid

AMR detection in the WGS era

Professor John Rossen, Medical Molecular Microbiologist, University of Groningen, The Netherlands

PLENARY SESSION: PUBLIC POLICY AND PUBLIC PERCEPTION - HOW IT IS SHAPED AND INFORMED

Antimicrobial resistance: how journalism can help

Ms Madlen Davies, Health and science editor, The Bureau of Investigative Journalism

Public perception of antimicrobials and AMR – how it is shaped and informed

Dr Laurie Denyer Willis, Research Fellow, London School of Hygiene and Tropical Medicine

Parallel Session One: New Initiatives to Support AMR Innovation

Public health driven R&D of antibiotics for priority drug resistant infections

Dr Seamus O'Brien, R&D Director, Global Antibiotic R&D Partnership (GARDP)

CARB-X: Building A Portfolio of New Antibiotics, Vaccines & Diagnostics with Open Science

Dr Richard Lawson, Director of the CARB-X Program Management Office

Swab and send – discovering new antimicrobials from natural products

Dr Adam Roberts, Senior lecturer, Liverpool School of tropical Medicine

Parallel Session two: Vaccines

What's new in conjugate vaccine development against infectious disease

Dr Viliam Pavliak, Senior Advisor, International Vaccine Institute

The global roadmap for STI vaccine development - state of the art review

Dr David McIntosh, Honorary Clinical Senior Lecturer, Imperial College London

The of Role of Vaccines in Preventing AMR

Dr Rajeka Lazarus, Consultant in Microbiology and Infectious Diseases, Bristol

PLENARY SESSION: DEBATE: CONSERVATION OF ANTIBIOTICS - RESERVING VERSUS HETEROGENICITY

Conservation of antibiotics is the ONLY way forward

Heterogencity: A little bit of everything will work wonders - cycling antibiotics is the future!

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Defeating AMR: The trinity of prevention, preservation & promotion

You will find links to the slide sets below.

MONDAY 12 MARCH

Welcome and Opening Remarks

Professor Dilip Nathwani OBE

KEYNOTE PRESENTATION

Global epidemiology of infectious diseases and AMR and the role of informatics

Professor Michael Osterholm

PLENARY SESSION: HOW CAN VACCINES AND DIAGNOSTICS TO HELP WIN THE BATTLE AGAINST AMR?

Global burden of bacterial infections: the role of vaccines in reducing AMR

Dr David McIntosh

Enabling the adoption of new diagnostics within the UK healthcare system

Dr Fiona Carragher

PLENARY SESSION: PRESERVING ANTIBIOTIC EFFICACY THROUGH EFFECTIVE PRESCRIBING: WHAT CAN WE LEARN FROM STEWARDSHIP IN LMICS?

Stewardship in Kerala, India

Dr Sanjeev Singh

Experiences from Latin America

Dr Gabriel Levy Hara

Stewardship in Africa - challenges and opportunities

Dr Brian Godman

SPONSORED SYMPOSIUMS

Diagnostic testing for point of care C Reactive Protein and how it can guide antibiotic prescribing

Supported by Abbott

BEYOND EMPERICAL THERAPY - Clinical Experiences with Fast Antibiotic Susceptibility Testing

Technology overview - The Accelerate Pheno™ System

Steve Holland

Clinical Experiences of the Accelerate Pheno™ System at an NHS District General Hospital

Dr Claire Thomas

PARALLEL SESSION - Routine and rapid surveillance systems

What surveillance do we have for AMR?

Dr Berit Muller-Peabody

Why is surveillance important after introducing vaccines?

Dr Michael Edelstein

Rapid surveillance in emergency situations: The Zika Experience

Professor Jimmy Whitworth

Legacy planning – what did we learn from Ebola

Dr Timothy Brooks

PARALLEL SESSION - The quiet revolution: the modernisation of laboratories - optimal use of existing diagnostics

Procalcitonin – lessons and limitations

Dr Stephan Harbarth

MALDI-TOF and its impact on patient care

Dr Savita Gossain

Syndromic approaches to infection detection - TaqMan array cards

Dr Martin Curran

PARALLEL SESSION - Successful stewardship across multidisciplinary settings

Alternative models of care: Nurses in antimicrobial stewardship

Jo McEwen

Successful stewardship in hospital settings (HDU and general)

Dr Charles Luyt

Antimicrobial stewardship in long term care facilities (LTCFs)

Dr Elizabeth Beech

PARALLEL SESSION - Global surveillance of resistance & antibiotic prescribing quality

Global Antimicrobial Resistance Surveillance System (GLASS)

Professor Roman Kozlov

Global PPS

Professor Herman Goossens

TUESDAY 13 MARCH

PLENARY SESSION: VACCINES AND DIAGNOSTICS – WHAT DOES THE FUTURE HOLD?

New Vaccines against Epidemic Infectious Diseases

Dr David McIntosh

PARALLEL SESSION - Innovation: Rapid diagnostics and emerging therapies

New for old and emerging treatments - a summary of new agents in development

Professor Alasdair MacGowan

Clinical need for rapid diagnostic tests

Professor Herman Goossens

Skin patch antibiotics - the next big thing?

Professor Ryan Donnelly

Harnessing the host-protein response to distinguish between bacterial and viral infections

Dr Liran Shani

Lefamulin: the potential for one antibiotic rather than two in CABP

Professor Mark Wilcox

PARALLEL SESSION - Next generation Antimicrobial Susceptibility Testing of Bacteria

Rapid susceptibility testing: new phenotypic and non-WGS genotypic approaches

Dr Oskar Ekelund

WGS-based susceptibility testing for TB: from research to service delivery

Professor Grace Smith

Should WGS be used for susceptibility testing of bacteria other than TB?

Dr Matthew Ellington

GARROD LECTURE

Preparing for the Black Swans of resistance

Professor David Livermore

KEYNOTE LECTURE

Progressing the new essential medicines agenda

Professor Celine Pulcini

Reporting Guidelines Workshop

Use of reporting guidelines to design, report and referee antibiotic stewardship studies

Dr Sheldon Stone

PARALLEL SESSION

Latest clinical data and early experience of managing difficult-to-treat Gram-negative infections with a novel β-lactamase inhibitor combination

Supported by Pfizer

PARALLEL SESSION

Current thinking about cephalosporins and CDI & AMR. Can a new cephalosporin help?

Supported by Cardiome

CLOSING PLENARY SESSION - NOVEL GLOBAL EDUCATIONAL OPPORTUNITIES

Delivering open access, high impact-low cost education to all

Professor Dilip Nathwani OBE

Developing a global community of practice

Dr Elizabeth Tayler

Multi-drug resistance gram negative infections.
You will find links to the slide sets below.

Welcome

Professor Dilip Nathwani OBE, President, BSAC

The current global and UK epidemiology of GNB infections

Professor Timothy Walsh, Professor of Medical Microbiology and Antibiotic Resistance, Cardiff University

Burden and current global management on GNB infections: Lessons from a global PPS

Dr Ann Versporten, Global PPS Coordination Centre, University of Antwerp, Antwerp

Clinical presentations and impact of GNB infections in the UK

Dr Gavin Barlow, Infectious Diseases Consultant, Hull & East Yorkshire Hospitals NHS Trust

Hospital antibiotic prescribing to minimise AMR - the Antibiotic Reduction Kit (ARK-Hospital) Programme

Professor Martin Llewelyn, Reader in Infectious Diseases, Brighton and Sussex Medical School

NDM, ESBL and KPC - the US experience

Dr Lilian Abbo, Chief Infection Prevention & Antimicrobial Stewardship JHS President WIAM Advisory Board UMMSM, Jackson Health System, University of Miami, United States

UK Guidelines for GNB infections

Professor Peter Hawkey, PHE Lead Public Health Microbiologist, Heart of England NHS Foundation Trust, Birmingham UK

Optimising PK/PD for treatment of GNB

Dr Federico Pea, Institute of Clinical Pharmacology, University Teaching Hospital of Udine, Italy

Advances in beta-lactamase inhibition in difficult-to-treat infections due to aerobic Gram-negative bacteria

Dr Andrew Dodgson, Consultant Microbiologist and Infection Control Doctor, Manchester Royal Infirmary & Dr Matthew Dryden, Consultant in Microbiology and Communicable Disease, Hampshire Hospitals Foundation Trust

A randomised controlled trial evaluating the TARGET (Treat Antibiotics Responsibly, Guidance, Education, Tools) Antibiotics toolkit

Miss Leah Jones, Trainee Health Psychologist & Research Assistant, Public Health England

Rapid phenotypic susceptibility testing of bacteria: SLIC by name and slick by nature

Dr Robert Hammond, Post Doctoral Research Fellow, University of St Andrews

Quality indicators and quantity metrics for responsible antibiotic use, lessons from DRIVE-AB

Dr Vera Vlahović-Palčevski, Clinical Pharmacologist, DRIVE-AB & University of Rijeka, Croatia

UK approach to use of metrics and targets for GNB infections

Dr Susan Hopkins, Consultant in Infectious Diseases & Microbiology, Royal Free Hospital, NHS Trust, London

GNB infections and stewardship

Professor Dilip Nathwani OBE, Consultant Physician and Honorary Professor of Infection, University of Dundee, Dundee UK

Prevention of GNB infections

Professor Peter Wilson, Consultant Microbiologist, UCHL Foundation NHS Trust, London

Drug discovery to combat GNB infections: current challenges and possible progress

Professor Mike Ferguson, Regius Professor and Associate Dean for Research Strategy, Biologicial Chemistry and Drug Discovery, University of Dundee, Dundee UK

BSAC AGM

Professor Dilip Nathwani OBE, President, BSAC

BSAC Virtual Learning Environment

Professor Dilip Nathwani OBE, President, BSAC & Mr Mark Lester, FutureLearn

BSAC Spring Conference 2016: Start Smart Then Focus! Infection challenges and better outcomes: Is better implementation the missing link?

Presentation Details Downloads

The UK 5-year AMR Strategy – a brief overview

Dr Berit Muller-Pebody

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The Antimicrobial Managment Team [AMT] view

Dr Philip Howard

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The prescriber view

Dr Thomas Johnston

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How can improvement science contribute to the AMR agenda in the “real world setting”: instructive studies illustrating helpful tips for the busy practitioner?

Professor Nick Sevdalis

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Improvement science: Adapting your strategy to ensure success

Dr Mike Cooper

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Matching Michigan: Lessons in reducing central line infections in the Intensive Care Unit

Dr Carolyn Tarrant

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Clinical Practice as behaviour: How can we use this concept to improve sepsis care?

Dr Fabiana Lorencatto

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Amikacin to achieve clinical cure in adults with gram negative infections. Are therapeutic levels associated with effectiveness and adverse effects?

Dr Abi Jenkins

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Development of an antimicrobial stewardship plan in regional medication chart for use with adult patients in an acute setting with separate antimicrobial section

Dr Caroline Mallon

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Carbapenemase producing enterobactericeae screening: assessing local knowledge to a global threat

Dr Georgina Beckley

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Rapid phenotypic susceptibility testing of bacteria: SLIC by name and slick by nature

Mr Robert J H Hammond

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The GOTARGET Study: An evaluation of the TARGET (Treat Antibiotics Responsibly; Guidance, Education, Tools) Antibiotics Toolkit to improve antimicrobial stewardship in primary care using the Normalisation Process Theory

Ms Leah Jones

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THE GARROD LECTURE – The role of the epidemiologist in antimicrobial chemotherapy

Professor John McGowan

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CLOSING DEBATE: Surviving Sepsis and stewardship – a double edged sword?

Question: Start Smart then Focus – are these hopelessly competing objectives?
For: Dr David Jenkins, Consultant Medical Microbiologist, University Hospitals Leicester, Leicester
Against: Professor Alasdair McGowan, Professor of Clinical Microbiology and Antimicrobial Therapeutics, Southmead
Hospital, Bristol

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Antibacterial dosing in obese patients – challenges and pragmatic approaches

Dr Alison Thomson, Senior Lecturer, University of Strathclyde

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Pharmacological management of viruses in obese patients

Dr Dimitar Tonev, Director Medical Aff airs UK, Ireland and Nordics, Cubist International

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Antifungal PK/PD – the challenges posed by obesity

Professor William Hope, Professor of Therapeutics & Infectious Diseases, University of Liverpool

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Obesity as a risk factor for complicated antimicrobial therapy: a prospective cross-sectional study

Ms Esmita Charani, Health Protection Research Unit, Imperial College London

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Development and Evaluation of Bayesian Software for Improving Therapeutic Drug Monitoring of Gentamicin in Neonates

Dr Joe Standing, UCL Institute of Child Health/Great Ormond Street Hospital

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Informing future surveillance for carriage of multi-resistant gram negative bacteria: problems with recruiting to an English stool sample cross-sectional community prevalence study

Mrs Linda Crocker, Public Health England Primary Care Unit, Gloucestershire Royal Hospital

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Meropenem Review and De-escalation in a Tertiary Teaching Hospital

Dr. Úna NíRiain, University Hospital Galway, Newcastle Rd, Galway

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Antimicrobial resistance: Linking future prescribers and patients through near peer education

Dr Carwyn Watkins, Royal Devon and Exeter Hospital

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Why Is Improvement Difficult?

Professor Peter Davey, Lead for Clinical Quality Improvement, University of Dundee

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The challenges of antimicrobial prescribing in an ageing population

Professor Colin P Bradley, Professor and Head of Department of General Practice, University College Cork

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Antimicrobial prescribing in paediatrics – what collateral damage?

Professor Mike Sharland, Paediatric Infectious Diseases Research Group, St Georges University, London

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The use and abuse of antibiotics during pregnancy

Professor Ronald F Lamont, Emeritus Consultant in Obstetrics & Gynaecology, North West Thames NHS Trust & Hon Reader, Division of Surgery, University College London

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BSAC Spring Conference 2014: Antimicrobial stewardship in human and animal health

Presentation Details Downloads

What is antimicrobial stewardship? The current landscape

Professor Peter Davey, Dundee

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The future landscape – are we interpreting stewardship correctly and what could we do differently?

Dr David Jenkins, Leicester

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Antimicrobial stewardship in veterinary medicine

Mr Peter Jones, Immediate Past President, British Veterinary Association

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A Community Outbreak of New Delhi Metallo-beta-lactamase-1 (NDM-1) Escherichia coli in Scotland: Implications for Antimicrobial Stewardship

Dr Nigel Calvert, Dumfries

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A qualitative approach to explore motivations for antimicrobial prescribing by veterinary surgeons in UK pig practice

Miss Lucy Coyne, Liverpool

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The development and evaluation of a peer education workshop for school aged children on hygiene and the prevention of infection

Dr Vicki Young, Gloucester

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Development of the first national antimicrobial prescribing and stewardship competences

Dr Diane Ashiru-Oredope, London

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The Garrod Lecture 2014:
Antimicrobial Susceptibility Testing – are we heading towards global standardisation?

Professor Gunnar Kahlmeter, Sweden

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Inflammatory and other surrogate markers in assessing bacterial infections and aiding prescribing decisions

Professor Stephan Harbarth, Geneva

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No action about us without us – importance of driving professional behaviour change in successfully implementing new technologies and stewardship strategies

Professor Susan Michie, Health Psychologist, UCL, London

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BSAC Spring Meeting 2013: Gram negative, gram positive, fungal and beyond – the increasing complexities of “everyday” infections

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What is happening now? Epidemiology of resistance

Professor Neil Woodford, London

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Carbapenemases in pratice – lessons learnt from spread in our patch, prophylaxis and first/second line treatments

Dr Andrew Dodgson, Manchester

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Pseudomonas in augmented care – should we worry?

Dr Michael Kelsey, London

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Neisseria gonorrhea – the first untreatable infection

Professor Catherine Ison, London

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Susceptibility testing for vancomycin in staph aureus – what do we do now

Dr Robin Howe, Cardiff

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VRE – one difficult Gram positive after another. Treatment options for severe infections

Dr Nick Brown, Cambridge

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Increase in transrectal ultrasound guided prostate biopsy associated infection; is a change in antimicriobial prophylaxis the solution?

Dr Cliodhna Ni Bhuachalla, Dublin

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Antibiotic Management of Neutropenic Sepsis at The James Cook University Hospital

Dr Katherine Watson, Middlesborough

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Optimisation of combination therapy for treatment of Pseudomonas aeruginosa

Dr Alexandra Cochrane, Bristol

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The Perils of Medical Tourism

Dr Theodore Gouliouris, Cambridge

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Directed therapy for fungal infections – latest advances

Professor Rosemary Barnes, Cardiff

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News uses for old agents

Dr Kieran Hand, Southampton

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Welcome address: 40 years of BSAC

Professor Peter Davey, Dundee

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Session one: National methods and surveillance

BSAC antimicrobial susceptibility testing – from Stokes to European harmonization to world?

Dr Derek Brown, Cambridge

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Antimicrobial resistance surveillance, improving relevance and outputs

Professor Alasdair MacGowan, Bristol

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Antimicrobial stewardship – a tool for improving outcomes?

Professor Alison Holmes, London

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Resistance in farm animals – implications for animal and public health

Mr Jeff Jones, Veterinary Laboratories Agency
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Session two: Challenges and prospects: what now for multi-drug resistant infections?

Acinetobacter and more…

Professor Mark Pallen, Birmingham

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The Garrod Lecture: My 40 years – from penicillin-binding proteins to molecular epidemiology

Professor Brian G Spratt, London

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Session three: 20th – 21st century practice

Antimicrobial chemotherapy in practice from 20th to 21st century – throughout my years as a physician

Professor Alasdair Geddes, Birmingham

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The rise of the antimicrobial pharmacist

Dr Kieran Hand, Southampton

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Session four: What next for antimicrobial therapy?

So what is the future?

Professor Roger Finch, Nottingham

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A view from Industry: Past, present and prospects for the future

Richard Bax, Reading

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The next 40 years?

Professor Laura Piddock, Birmingham

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